Have you ever wondered about this?
The Great Oxygenation Event (GOE, also called the oxygen catastrophe or oxygen crisis or Great Oxidation) was the appearance of free oxygen (O2) in Earth's atmosphere. This major environmental change happened around 2,400.The rising oxygen levels may have wiped out a huge portion of the Earth's inhabitants at the time. From their perspective it was a catastrophe. Cyanobacteria were essentially responsible for probably the largest extinction event in Earth's history.
http://en.wikipedia.org/wiki/Great_Oxygenation_Event

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